Clinical Research
Clinical research projects
Name of the Project |
Principal Investigators |
Supported by |
Duration |
A Double-Masked, Randomized, Controlled Phase 3 Study of the Efficacy, Safety, and Tolerability of Repeated Intravitreal Administration of VEGF Trap-Eye in Subjects with Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO) |
Dr. Raja Narayanan |
Regeneron Pharmaceuticals Inc. |
2008 onwards |
ENDURE Study |
Dr. Somasheila Murthy |
Novartis |
2010 onwards |
MMT Study |
Dr Vanita Pathak |
Allergan |
2010 onwards |
CMV retinitis |
Dr Annie Mathai |
University of Pennsylvania |
2010 onwards |
A randomised double-masked active controlled phase 3 study of the efficacy, safety and tolerability of repeated doses of intravitreal VEGF trap-eye in subjects with neovascular age related macular degeneration (AMD) VEGF TRAP study |
Dr Raja Narayanan |
Bayer HealthCare, Germany |
2008-2011 |
Comparative, randomized, open trial on the anti-inflammatory efficacy of diclofenac released from an intra ocular lens versus administration of 0.1% diclofenac eye-drops in the prevention of post operative inflammatory manifestations after cataract surgery. – Ancillary study: 1 year follow-up of the safety |
Dr Virender S Sangwan |
IOL Tech Carl Zeiss MediTec, France |
2006-2011 |
A phase 2/3 randomised, controlled double-masked multi-center comparitive trial in parallel groups to compare the safety and efficacy of intravitreous injections of 0.3 mg pegaptanib sodium (Macugen) given as often as every 6 weeks for 2 years, to sham injections in subjects with Diabetic Macular Edema (DME) involving the center of the macula |
Dr Subhadra Jalali |
Pfizer, USA |
2006-2012 |
Comparison of postoperative refractive outcomes after calculation of IOL power using the IOL master and ultrasound biometry |
Dr Sujata Das |
Hyderabad Eye Research Foundation, India |
2009 onwards |
A phase II prospective, randomised, multi-center, diabetic vascular edema dose ranging, comparator study evaluating the efficacy and safety of PF-04523655 versus laser therapy (DEGAS) |
Dr Soumyava Basu |
Pfizer, USA |
2009 onwards |
A study of unilateral retinoblastoma with and without histopathologic high-risk features and the role of adjuvant chemotherapy – a groupwide phase III study |
Dr Santosh G Honavar |
National Childhood Cancer Foundation, USA |
2009-2011 |
Indian Council of Medical Research National Retinoblastoma Registry |
Dr Santosh G Honavar |
Indian Council of Medical Research, India |
2009 onwards |